WebGrab the helm and go on an adventure in Google Earth. WebJan 23, 2024 · Using a novel chemical procedure developed in her lab, Yimon Aye and her group are helping to blaze a trail in the emerging field of precision medicine by targeting and modulating single proteins to achieve desired responses. The procedure, targetable reactive electrophiles and oxidants – dubbed “T-REX” by the group – involves the use of a …
Hiding in Plain Sight: The Issue of Hidden Variables
WebYimon Aye ( Burmese: ရည်မွန်အေး; born 12 July 1980 [1] in Burma) is an American chemist and molecular biologist. Currently she is an Associate Professor of chemistry at EPFL. [2] Career [ edit] Aye spent her early life in Burma. WebMar 31, 2024 · Earth isn’t perfectly round. Earth is thicker around the equator, the belt around the middle. How much thicker? Well, it’s about 0.3% thicker. It’s not much, so … cancer treatment center of america schaumburg
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WebDespite the known propensity of small-molecule electrophiles to react with numerous cysteine-active proteins, biological actions of individual signal inducers have emerged to be chemotype-specific. To pinpoint and quantify the impacts of modifying one target out of the whole proteome, we develop a target-protein-personalized “electrophile toolbox” with … WebMar 23, 2016 · Proximity enhancement is a central chemical tenet underpinning an exciting suite of small-molecule toolsets that have allowed us to unravel many biological complexities. The leitmotif of this opus is "tethering"-a strategy in which a multifunctional small molecule serves as a template to bring prote … WebJan 26, 2024 · Reactive metabolite sensing is emerging as a key regulatory element (1–3).In this paradigm, specific sensor proteins, or privileged first responders, are modulated by native electrophilic metabolite signals largely without enzyme assistance (2, 4).These individual protein-specific substoichiometric electrophile-labeling events may drive either … cancer treatment center america philadelphia