Phospho-acss2

WebNutritional stresses, which restrict acetyl-CoA production from glucose or acetate uptake, result in AMPK-mediated phosphorylation and nuclear translocation of ACSS2. ACSS2 binds to TFEB, translocates to lysosomal and autophagosomal gene promoter regions, and incorporates acetate from histone acetylation turnover to locally produce acetyl-CoA for … WebNov 23, 2024 · ACSS2 enables cholesterol synthesis in the cytoplasm, which is trafficked to the surface to provide mechanical tenacity. GM3-IRE1-sXBP1-ACSS2-cholesterol axis is …

HDAC3 is a molecular brake of the metabolic switch supporting ... - Nature

WebImportantly, we show that ACSS2 Ser-267 phosphorylation regulates its stability by reducing polyubiquitination and degradation. ACSS2 Ser-267 is critical for OGT-mediated GBM … Webphospho-Acetyl Coenzyme A Carboxylase beta Ser22 antibody (PE) Size Price Qty. 100 μl. $443.80. Add to Cart. Availability. Request Lead Time; In stock and ready for quick dispatch; Usually dispatched within 2 to 3 weeks. Shipping Destination: fixing glue https://jenniferzeiglerlaw.com

Anti-ACSS2 Antibody (A-9) SCBT - Santa Cruz Biotechnology

WebJul 21, 2024 · To silence Acly and Acss2, cells were infected with 50 MOI shACLY/shACSS2 adenovectors (Vector BioLabs). To perform co-silencing of Hdac3 and Acly/Acss2, cells at the induction of differentiation ... WebJun 7, 2024 · The authors monitored ACSS2 subcellular localization in human glioblastoma cells and observed that cytosolic ACSS2 translocated into the nucleus when the cells … WebJun 1, 2024 · ACSS2 is phosphorylated at Ser659 by AMPK and then forms a translocation complex with Importin α5 to translocate into the nucleus. This process interacts with TFEB, resulting in upregulated... can my family see my icloud photos

Acid phosphatase 2 (ACP2) is required for membrane fusion …

Category:Phospholipase A2 Receptor - an overview ScienceDirect Topics

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Phospho-acss2

(orb1096966) ACSS2(Phospho-Ser659) Antibody - Biorbyt - CiteAb

Web(orb1096966) ACSS2 (Phospho-Ser659) Antibody Sign in or register to save this reagent to your favourites Supplier Biorbyt Host Rabbit Type Primary Clonality Polyclonal Conjugate … WebMay 31, 2024 · A decrease in ACSS2 lowers nuclear acetyl-CoA levels, histone acetylation, and responsive expression of the cohort of neuronal genes. In adult mice, attenuation of hippocampal ACSS2 expression ...

Phospho-acss2

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WebJan 21, 2024 · We interrogate whether ACSS2 can facilitate the local transfer of acetyl groups. Our results point to direct transfer of intact acetate that is mediated by ACSS2, underscoring a critical function of acetate transfer in using local and nuclear acetate pools for histone acetylation and rapid transcriptional activation. Web(orb1096966) ACSS2 (Phospho-Ser659) Antibody Sign in or register to save this reagent to your favourites Supplier Biorbyt Host Rabbit Type Primary Clonality Polyclonal Conjugate Unconjugated Modification Phospho (Ser659) View Product On Supplier's Website Request a Quote from Biorbyt Supplier provided information Validations None provided

WebAnti-ACSS2 Antibody (A-9) is a mouse monoclonal IgG 1 κ ACSS2 antibody, cited in 5 publications, provided at 200 µg/ml raised against amino acids 1-160 mapping at the N-terminus of ACSS2 of human origin Anti-ACSS2 Antibody (A-9) is recommended for detection of ACSS2 of mouse, rat and human origin by WB, IP, IF and ELISA Web3.1.3 Phospholipase A2 Inhibition. Phospholipase A2 (PLA2), which cleaves phospholipids producing lysophospholipids and free fatty acids, was originally identified as an …

WebMar 21, 2024 · ACSS2 (Acyl-CoA Synthetase Short Chain Family Member 2) is a Protein Coding gene. Diseases associated with ACSS2 include Orofacial Cleft 1 and … WebSep 18, 2024 · Acss2 Deletion Protects Against Lipid Deposition and Obesity. To gain insight into the normal physiological function of ACSS2, we compared Acss2 -null mice with …

WebIn the nucleus, ACSS2 binds to transcription factor EB and translocates to lysosomal and autophagy gene promoter regions, where ACSS2 incorporates acetate generated from …

WebJul 7, 2024 · ACSS2 has been found to primarily undergo translocation from the cytoplasm to the nucleus . ACSS2 translocation is tightly connected with hormonal and transcription … can my fallopian tubes hurtWebJun 11, 2024 · Abstract. Autophagy is an intracellular degenerative pathway which is responsible for neuronal survival. Under the condition of nutrient deprivation, autophagy can lead to dysfunction in memory consolidation. … can my family come to my showsWebACSS2 / ACAS2 is a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate ... can my fashion line be called lola lemonWebDeacetylates ACSS2 leading to its activation, and HMGCS1. Involved in liver and muscle metabolism. ... All lanes : Anti-SIRT1 (phospho T530) antibody [EPNCIR153] (ab156585) at 1/1000 dilution Lane 1 : 293T cell lysates Lane 2 : 293T cell lysates treated with Calyculin A Lysates/proteins at 10 µg per lane. Secondary fixing gold ribbon cablesWebMay 25, 2024 · In the nucleus, ACSS2 binds to transcription factor EB and translocates to lysosomal and autophagy gene promoter regions, where ACSS2 incorporates acetate generated from histone acetylation turnover to locally produce acetyl-CoA for histone H3 acetylation in these regions and promote lysosomal biogenesis, autophagy, cell survival, … can my family member use my bj\u0027s cardWebACSS2 Antibodies. Santa Cruz Biotechnology, Inc. offers a broad range of ACSS2 antibodies. Select ACSS2 antibodies from monoclonal antibodies listed below. View … can my family use usaaWebDownload scientific diagram Cdk5 and p35 are important for proliferation of human TT cells. A, lysates of TT cells were immunoblotted by specific antibodies of Cdk5 and p35 with variant loading ... can my favorite shapes be alphabetized